| Date | Home | Away | Result |
|---|---|---|---|
| 15/09/15 19:45 | Middlesbrough FC | Brentford FC | 3-1 |
| 15/09/15 19:45 | Brighton and Hove Albion | Rotherham United | 2-1 |
| 15/09/15 19:45 | Preston North End | Bristol City | 1-1 |
| 15/09/15 19:45 | Birmingham City | Nottingham Forest | 0-1 |
| 15/09/15 19:45 | Cardiff City | Hull City A.F.C. | 0-2 |
| 15/09/15 19:45 | Burnley FC | Milton Keynes Dons FC | 2-1 |
| 15/09/15 19:45 | Leeds United | Ipswich Town | 0-1 |
| 15/09/15 19:45 | Charlton Athletic | Huddersfield Town | 1-2 |
| 15/09/15 20:00 | Bolton Wanderers | Sheffield Wednesday | 0-0 |
| 15/09/15 20:00 | Reading FC | Derby County | 0-1 |
| 16/09/15 19:45 | Queens Park Rangers | Blackburn Rovers | 2-2 |
| 29/09/15 19:45 | Fulham FC | Wolverhampton Wanderers | 0-3 |