| Date | Home | Away | Result |
|---|---|---|---|
| 12/01/16 19:45 | Rotherham United | Brighton and Hove Albion | 2-0 |
| 12/01/16 19:45 | Huddersfield Town | Charlton Athletic | 5-0 |
| 12/01/16 19:45 | Derby County | Reading FC | 1-1 |
| 12/01/16 19:45 | Milton Keynes Dons FC | Burnley FC | 0-5 |
| 12/01/16 19:45 | Ipswich Town | Leeds United | 2-1 |
| 12/01/16 19:45 | Blackburn Rovers | Queens Park Rangers | 1-1 |
| 12/01/16 19:45 | Bristol City | Preston North End | 1-2 |
| 12/01/16 19:45 | Brentford FC | Middlesbrough FC | 0-1 |
| 12/01/16 19:45 | Sheffield Wednesday | Bolton Wanderers | 3-2 |
| 12/01/16 19:45 | Nottingham Forest | Birmingham City | 1-1 |
| 12/01/16 20:00 | Wolverhampton Wanderers | Fulham FC | 3-2 |
| 13/01/16 19:45 | Hull City A.F.C. | Cardiff City | 2-0 |