| Date | Home | Away | Result |
|---|---|---|---|
| 20/10/15 19:45 | Cardiff City | Middlesbrough FC | 1-0 |
| 20/10/15 19:45 | Hull City A.F.C. | Ipswich Town | 3-0 |
| 20/10/15 19:45 | Brighton and Hove Albion | Bristol City | 2-1 |
| 20/10/15 19:45 | Rotherham United | Reading FC | 1-1 |
| 20/10/15 19:45 | Charlton Athletic | Preston North End | 0-3 |
| 20/10/15 19:45 | Nottingham Forest | Burnley FC | 1-1 |
| 20/10/15 19:45 | Huddersfield Town | Milton Keynes Dons FC | 2-0 |
| 20/10/15 19:45 | Queens Park Rangers | Sheffield Wednesday | 0-0 |
| 20/10/15 20:00 | Bolton Wanderers | Birmingham City | 0-1 |
| 21/10/15 19:45 | Wolverhampton Wanderers | Brentford FC | 0-2 |
| 21/10/15 19:45 | Fulham FC | Leeds United | 1-1 |
| 21/10/15 19:45 | Blackburn Rovers | Derby County | 0-0 |