| Date | Home | Away | Result |
|---|---|---|---|
| 29/04/22 19:45 | Queens Park Rangers | Sheffield United | 1-3 |
| 30/04/22 12:30 | Barnsley FC | Preston North End | 1-3 |
| 30/04/22 15:00 | Nottingham Forest | Swansea City | 5-1 |
| 30/04/22 15:00 | Blackburn Rovers | AFC Bournemouth | 0-3 |
| 30/04/22 15:00 | FC Blackpool | Derby County | 0-2 |
| 30/04/22 15:00 | Bristol City | Hull City A.F.C. | 5-0 |
| 30/04/22 15:00 | Coventry City | Huddersfield Town | 1-2 |
| 30/04/22 15:00 | Middlesbrough FC | Stoke City | 3-1 |
| 30/04/22 15:00 | Millwall FC | Peterborough United | 3-0 |
| 30/04/22 15:00 | Reading FC | West Bromwich Albion | 0-1 |
| 30/04/22 15:00 | Cardiff City | Birmingham City | 1-1 |
| 02/05/22 17:15 | Fulham FC | Luton Town | 7-0 |