| Date | Home | Away | Result |
|---|---|---|---|
| 15/01/22 12:30 | Luton Town | AFC Bournemouth | 3-2 |
| 15/01/22 12:30 | Cardiff City | Blackburn Rovers | 0-1 |
| 15/01/22 15:00 | Derby County | Sheffield United | 2-0 |
| 15/01/22 15:00 | Fulham FC | Bristol City | 6-2 |
| 15/01/22 15:00 | Middlesbrough FC | Reading FC | 2-1 |
| 15/01/22 15:00 | Millwall FC | Nottingham Forest | 0-1 |
| 15/01/22 15:00 | Peterborough United | Coventry City | 1-4 |
| 15/01/22 15:00 | Preston North End | Birmingham City | 1-1 |
| 15/01/22 15:00 | Queens Park Rangers | West Bromwich Albion | 1-0 |
| 15/01/22 15:00 | Huddersfield Town | Swansea City | 1-1 |
| 16/01/22 12:00 | Hull City A.F.C. | Stoke City | 0-2 |
| 26/04/22 19:45 | Barnsley FC | FC Blackpool | 0-2 |