| Date | Home | Away | Result |
|---|---|---|---|
| 11/12/21 12:30 | Huddersfield Town | Coventry City | 1-1 |
| 11/12/21 15:00 | AFC Bournemouth | Blackburn Rovers | 0-2 |
| 11/12/21 15:00 | Derby County | FC Blackpool | 1-0 |
| 11/12/21 15:00 | Hull City A.F.C. | Bristol City | 2-2 |
| 11/12/21 15:00 | Luton Town | Fulham FC | 1-1 |
| 11/12/21 15:00 | Peterborough United | Millwall FC | 2-1 |
| 11/12/21 15:00 | Preston North End | Barnsley FC | 2-1 |
| 11/12/21 15:00 | Stoke City | Middlesbrough FC | 0-0 |
| 11/12/21 15:00 | West Bromwich Albion | Reading FC | 1-0 |
| 11/12/21 15:00 | Birmingham City | Cardiff City | 2-2 |
| 11/12/21 15:00 | Swansea City | Nottingham Forest | 1-4 |
| 05/04/22 19:45 | Sheffield United | Queens Park Rangers | 1-0 |