| Date | Home | Away | Result |
|---|---|---|---|
| 16/10/20 19:45 | Derby County | Watford FC | 0-1 |
| 17/10/20 15:00 | Swansea City | Huddersfield Town | 1-2 |
| 17/10/20 15:00 | Rotherham United | Norwich City | 1-2 |
| 17/10/20 15:00 | Wycombe Wanderers | Millwall FC | 1-2 |
| 17/10/20 15:00 | Blackburn Rovers | Nottingham Forest | 0-1 |
| 17/10/20 15:00 | AFC Bournemouth | Queens Park Rangers | 0-0 |
| 17/10/20 15:00 | Middlesbrough FC | Reading FC | 0-0 |
| 17/10/20 15:00 | Birmingham City | Sheffield Wednesday | 0-1 |
| 17/10/20 15:00 | Luton Town | Stoke City | 0-2 |
| 17/10/20 15:00 | Brentford FC | Coventry City | 2-0 |
| 17/10/20 15:00 | Barnsley FC | Bristol City | 2-2 |
| 18/10/20 12:00 | Preston North End | Cardiff City | 0-1 |