| Date | Home | Away | Result |
|---|---|---|---|
| 24/04/21 12:30 | AFC Bournemouth | Brentford FC | 0-1 |
| 24/04/21 15:00 | Queens Park Rangers | Norwich City | 1-3 |
| 24/04/21 15:00 | Watford FC | Millwall FC | 1-0 |
| 24/04/21 15:00 | Cardiff City | Wycombe Wanderers | 2-1 |
| 24/04/21 15:00 | Derby County | Birmingham City | 1-2 |
| 24/04/21 15:00 | Coventry City | Preston North End | 0-1 |
| 24/04/21 15:00 | Nottingham Forest | Stoke City | 1-1 |
| 24/04/21 15:00 | Barnsley FC | Rotherham United | 1-0 |
| 24/04/21 15:00 | Blackburn Rovers | Huddersfield Town | 5-2 |
| 24/04/21 15:00 | Middlesbrough FC | Sheffield Wednesday | 3-1 |
| 25/04/21 12:00 | Reading FC | Swansea City | 2-2 |
| 25/04/21 13:00 | Bristol City | Luton Town | 2-3 |