| Date | Home | Away | Result |
|---|---|---|---|
| 16/04/21 18:00 | Blackburn Rovers | Derby County | 2-1 |
| 16/04/21 18:00 | Reading FC | Cardiff City | 1-1 |
| 17/04/21 12:30 | Middlesbrough FC | Queens Park Rangers | 1-2 |
| 17/04/21 12:30 | Brentford FC | Millwall FC | 0-0 |
| 17/04/21 12:30 | Luton Town | Watford FC | 1-0 |
| 17/04/21 12:30 | Nottingham Forest | Huddersfield Town | 0-2 |
| 17/04/21 12:30 | Swansea City | Wycombe Wanderers | 2-2 |
| 17/04/21 12:30 | Sheffield Wednesday | Bristol City | 1-1 |
| 17/04/21 12:30 | Stoke City | Preston North End | 0-0 |
| 17/04/21 20:00 | Norwich City | AFC Bournemouth | 1-3 |
| 18/04/21 12:00 | Rotherham United | Birmingham City | 0-1 |
| 18/04/21 15:00 | Coventry City | Barnsley FC | 2-0 |