| Date | Home | Away | Result |
|---|---|---|---|
| 02/03/21 19:00 | Coventry City | Middlesbrough FC | 1-2 |
| 02/03/21 19:00 | Huddersfield Town | Birmingham City | 1-1 |
| 02/03/21 19:00 | Millwall FC | Preston North End | 2-1 |
| 02/03/21 19:00 | Cardiff City | Derby County | 4-0 |
| 02/03/21 19:45 | Nottingham Forest | Luton Town | 0-1 |
| 02/03/21 20:00 | Reading FC | Blackburn Rovers | 1-0 |
| 03/03/21 17:30 | Norwich City | Brentford FC | 1-0 |
| 03/03/21 19:00 | Watford FC | Wycombe Wanderers | 2-0 |
| 03/03/21 19:00 | Queens Park Rangers | Barnsley FC | 1-3 |
| 03/03/21 19:45 | Bristol City | AFC Bournemouth | 1-2 |
| 03/03/21 19:45 | Sheffield Wednesday | Rotherham United | 1-2 |
| 03/03/21 20:15 | Stoke City | Swansea City | 1-2 |