| Date | Home | Away | Result |
|---|---|---|---|
| 08/12/20 19:45 | Stoke City | Cardiff City | 1-2 |
| 08/12/20 19:45 | Watford FC | Rotherham United | 2-0 |
| 08/12/20 19:45 | Millwall FC | Queens Park Rangers | 1-1 |
| 08/12/20 19:45 | Swansea City | AFC Bournemouth | 0-0 |
| 08/12/20 19:45 | Huddersfield Town | Sheffield Wednesday | 2-0 |
| 08/12/20 19:45 | Coventry City | Luton Town | 0-0 |
| 09/12/20 19:00 | Preston North End | Middlesbrough FC | 3-0 |
| 09/12/20 19:45 | Brentford FC | Derby County | 0-0 |
| 09/12/20 19:45 | Norwich City | Nottingham Forest | 2-1 |
| 09/12/20 19:45 | Reading FC | Birmingham City | 1-2 |
| 09/12/20 19:45 | Barnsley FC | Wycombe Wanderers | 2-1 |
| 09/12/20 19:45 | Bristol City | Blackburn Rovers | 1-0 |