| Date | Home | Away | Result |
|---|---|---|---|
| 27/11/20 19:45 | Brentford FC | Queens Park Rangers | 2-1 |
| 28/11/20 12:30 | Reading FC | Bristol City | 3-1 |
| 28/11/20 15:00 | Watford FC | Preston North End | 4-1 |
| 28/11/20 15:00 | Sheffield Wednesday | Stoke City | 0-0 |
| 28/11/20 15:00 | Birmingham City | Millwall FC | 0-0 |
| 28/11/20 15:00 | Norwich City | Coventry City | 1-1 |
| 28/11/20 15:00 | Blackburn Rovers | Barnsley FC | 2-1 |
| 28/11/20 15:00 | Rotherham United | AFC Bournemouth | 2-2 |
| 28/11/20 15:00 | Derby County | Wycombe Wanderers | 1-1 |
| 28/11/20 15:00 | Huddersfield Town | Middlesbrough FC | 3-2 |
| 28/11/20 15:00 | Cardiff City | Luton Town | 4-0 |
| 29/11/20 12:00 | Nottingham Forest | Swansea City | 0-1 |