| Date | Home | Away | Result |
|---|---|---|---|
| 21/09/18 19:45 | Wigan Athletic | Bristol City | 1-0 |
| 22/09/18 15:00 | Stoke City | Blackburn Rovers | 2-3 |
| 22/09/18 15:00 | West Bromwich Albion | Millwall FC | 2-0 |
| 22/09/18 15:00 | Sheffield United | Preston North End | 3-2 |
| 22/09/18 15:00 | Nottingham Forest | Rotherham United | 1-0 |
| 22/09/18 15:00 | Reading FC | Hull City A.F.C. | 3-0 |
| 22/09/18 15:00 | Leeds United | Birmingham City | 1-2 |
| 22/09/18 15:00 | Middlesbrough FC | Swansea City | 0-0 |
| 22/09/18 15:00 | Aston Villa | Sheffield Wednesday | 1-2 |
| 22/09/18 15:00 | Derby County | Brentford FC | 3-1 |
| 22/09/18 15:00 | Ipswich Town | Bolton Wanderers | 0-0 |
| 22/09/18 17:30 | Queens Park Rangers | Norwich City | 0-1 |