| Date | Home | Away | Result |
|---|---|---|---|
| 23/10/18 19:45 | Norwich City | Aston Villa | 2-1 |
| 23/10/18 19:45 | Middlesbrough FC | Rotherham United | 0-0 |
| 23/10/18 19:45 | Birmingham City | Reading FC | 2-1 |
| 23/10/18 19:45 | Millwall FC | Wigan Athletic | 2-1 |
| 23/10/18 19:45 | Queens Park Rangers | Sheffield Wednesday | 3-0 |
| 23/10/18 19:45 | Sheffield United | Stoke City | 1-1 |
| 23/10/18 19:45 | Swansea City | Blackburn Rovers | 3-1 |
| 24/10/18 19:45 | Leeds United | Ipswich Town | 2-0 |
| 24/10/18 19:45 | Bristol City | Hull City A.F.C. | 1-0 |
| 24/10/18 19:45 | Preston North End | Brentford FC | 4-3 |
| 24/10/18 20:00 | West Bromwich Albion | Derby County | 1-4 |
| 24/10/18 20:00 | Bolton Wanderers | Nottingham Forest | 0-3 |