| Date | Home | Away | Result |
|---|---|---|---|
| 06/10/18 12:30 | Leeds United | Brentford FC | 1-1 |
| 06/10/18 15:00 | Norwich City | Stoke City | 0-1 |
| 06/10/18 15:00 | Middlesbrough FC | Nottingham Forest | 0-2 |
| 06/10/18 15:00 | Queens Park Rangers | Derby County | 1-1 |
| 06/10/18 15:00 | Millwall FC | Aston Villa | 2-1 |
| 06/10/18 15:00 | Birmingham City | Rotherham United | 3-1 |
| 06/10/18 15:00 | West Bromwich Albion | Reading FC | 4-1 |
| 06/10/18 15:00 | Preston North End | Wigan Athletic | 4-0 |
| 06/10/18 15:00 | Swansea City | Ipswich Town | 2-3 |
| 06/10/18 15:00 | Sheffield United | Hull City A.F.C. | 1-0 |
| 06/10/18 17:30 | Bolton Wanderers | Blackburn Rovers | 0-1 |
| 07/10/18 13:30 | Bristol City | Sheffield Wednesday | 1-2 |