| Date | Home | Away | Result |
|---|---|---|---|
| 20/02/18 19:45 | Sheffield United | Queens Park Rangers | 2-1 |
| 20/02/18 19:45 | Nottingham Forest | Reading FC | 1-1 |
| 20/02/18 19:45 | Aston Villa | Preston North End | 1-1 |
| 20/02/18 19:45 | Barnsley FC | Burton Albion | 1-2 |
| 20/02/18 19:45 | Middlesbrough FC | Hull City A.F.C. | 3-1 |
| 20/02/18 19:45 | Brentford FC | Birmingham City | 5-0 |
| 20/02/18 19:45 | Millwall FC | Sheffield Wednesday | 2-1 |
| 20/02/18 20:00 | Bolton Wanderers | AFC Sunderland | 1-0 |
| 21/02/18 19:45 | Derby County | Leeds United | 2-2 |
| 21/02/18 19:45 | Wolverhampton Wanderers | Norwich City | 2-2 |
| 21/02/18 19:45 | Ipswich Town | Cardiff City | 0-1 |
| 21/02/18 19:45 | Bristol City | Fulham FC | 1-1 |