| Date | Home | Away | Result |
|---|---|---|---|
| 26/09/17 19:45 | Nottingham Forest | Fulham FC | 1-3 |
| 26/09/17 19:45 | Middlesbrough FC | Norwich City | 0-1 |
| 26/09/17 19:45 | Ipswich Town | AFC Sunderland | 5-2 |
| 26/09/17 19:45 | Barnsley FC | Queens Park Rangers | 1-1 |
| 26/09/17 19:45 | Cardiff City | Leeds United | 3-1 |
| 26/09/17 19:45 | Millwall FC | Reading FC | 2-1 |
| 26/09/17 19:45 | Burton Albion | Aston Villa | 0-4 |
| 26/09/17 19:45 | Brentford FC | Derby County | 1-1 |
| 26/09/17 19:45 | Hull City A.F.C. | Preston North End | 1-2 |
| 26/09/17 19:45 | Bristol City | Bolton Wanderers | 2-0 |
| 27/09/17 19:45 | Birmingham City | Sheffield Wednesday | 1-0 |
| 27/09/17 19:45 | Sheffield United | Wolverhampton Wanderers | 2-0 |