| Date | Home | Away | Result |
|---|---|---|---|
| 13/09/16 19:45 | Preston North End | Cardiff City | 3-0 |
| 13/09/16 19:45 | Fulham FC | Burton Albion | 1-1 |
| 13/09/16 19:45 | Derby County | Ipswich Town | 0-1 |
| 13/09/16 19:45 | Leeds United | Blackburn Rovers | 2-1 |
| 13/09/16 19:45 | Norwich City | Wigan Athletic | 2-1 |
| 13/09/16 19:45 | Brighton and Hove Albion | Huddersfield Town | 1-0 |
| 13/09/16 19:45 | Sheffield Wednesday | Bristol City | 3-2 |
| 13/09/16 19:45 | Wolverhampton Wanderers | Barnsley FC | 0-4 |
| 13/09/16 19:45 | Queens Park Rangers | Newcastle United | 0-6 |
| 13/09/16 20:00 | Reading FC | Birmingham City | 0-0 |
| 14/09/16 19:45 | Aston Villa | Brentford FC | 1-1 |
| 14/09/16 19:45 | Rotherham United | Nottingham Forest | 2-2 |