| Date | Home | Away | Result |
|---|---|---|---|
| 18/10/16 19:45 | Leeds United | Wigan Athletic | 1-1 |
| 18/10/16 19:45 | Blackburn Rovers | Nottingham Forest | 2-1 |
| 18/10/16 19:45 | Fulham FC | Norwich City | 2-2 |
| 18/10/16 19:45 | Derby County | Brentford FC | 0-0 |
| 18/10/16 19:45 | Brighton and Hove Albion | Wolverhampton Wanderers | 1-0 |
| 18/10/16 19:45 | Queens Park Rangers | Bristol City | 1-0 |
| 18/10/16 19:45 | Barnsley FC | Newcastle United | 0-2 |
| 18/10/16 19:45 | Ipswich Town | Burton Albion | 2-0 |
| 18/10/16 19:45 | Birmingham City | Rotherham United | 4-2 |
| 18/10/16 20:00 | Reading FC | Aston Villa | 1-2 |
| 19/10/16 19:45 | Cardiff City | Sheffield Wednesday | 1-1 |
| 19/10/16 19:45 | Preston North End | Huddersfield Town | 3-1 |