Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 22/02/22 19:45 | 22/02/22 19:45 | Middlesbrough FC | West Bromwich Albion | 2-1 | 4 - 6 - 7 |
| 22/02/22 19:45 | 22/02/22 19:45 | Preston North End | Nottingham Forest | 0-0 | 6 - 6 - 4 |
| 22/02/22 19:45 | 22/02/22 19:45 | Bristol City | Coventry City | 1-2 | 4 - 5 - 7 |
| 22/02/22 19:45 | 22/02/22 19:45 | Hull City A.F.C. | Barnsley FC | 0-2 | 3 - 7 - 10 |
| 22/02/22 20:00 | 22/02/22 20:00 | Reading FC | Birmingham City | 2-1 | 4 - 6 - 6 |
| 23/02/22 19:45 | 23/02/22 19:45 | Derby County | Millwall FC | 1-2 | 4 - 7 - 8 |
| 23/02/22 19:45 | 23/02/22 19:45 | Fulham FC | Peterborough United | 2-1 | 3 - 10 - 10 |
| 23/02/22 19:45 | 23/02/22 19:45 | Queens Park Rangers | FC Blackpool | 2-1 | 3 - 9 - 10 |
| 23/02/22 19:45 | 23/02/22 19:45 | Sheffield United | Blackburn Rovers | 1-0 | 4 - 5 - 7 |
| 23/02/22 19:45 | 23/02/22 19:45 | Huddersfield Town | Cardiff City | 2-1 | 3 - 9 - 9 |
| 23/02/22 19:45 | 23/02/22 19:45 | Stoke City | Luton Town | 1-2 | 4 - 7 - 6 |
| 26/04/22 19:45 | 26/04/22 19:45 | Swansea City | AFC Bournemouth | 3-3 | 8 - 5 - 4 |