Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 19/11/21 19:45 | 19/11/21 19:45 | Queens Park Rangers | Luton Town | 2-0 | 4 - 6 - 8 |
| 20/11/21 12:30 | 20/11/21 12:30 | Sheffield United | Coventry City | 0-0 | 4 - 6 - 5 |
| 20/11/21 15:00 | 20/11/21 15:00 | Stoke City | Peterborough United | 2-0 | 3 - 8 - 10 |
| 20/11/21 15:00 | 20/11/21 15:00 | Bristol City | Blackburn Rovers | 1-1 | 5 - 6 - 4 |
| 20/11/21 15:00 | 20/11/21 15:00 | Fulham FC | Barnsley FC | 4-1 | 3 - 10 - 10 |
| 20/11/21 15:00 | 20/11/21 15:00 | Huddersfield Town | West Bromwich Albion | 1-0 | 6 - 5 - 4 |
| 20/11/21 15:00 | 20/11/21 15:00 | Preston North End | Cardiff City | 1-2 | 4 - 7 - 9 |
| 20/11/21 15:00 | 20/11/21 15:00 | Swansea City | FC Blackpool | 1-1 | 3 - 9 - 10 |
| 20/11/21 15:00 | 20/11/21 15:00 | Hull City A.F.C. | Birmingham City | 2-0 | 6 - 5 - 5 |
| 20/11/21 15:00 | 20/11/21 15:00 | Middlesbrough FC | Millwall FC | 1-1 | 4 - 6 - 7 |
| 20/11/21 15:00 | 20/11/21 15:00 | Reading FC | Nottingham Forest | 1-1 | 4 - 6 - 5 |
| 21/11/21 12:00 | 21/11/21 12:00 | Derby County | AFC Bournemouth | 3-2 | 9 - 7 - 4 |