Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 29/10/21 19:45 | 29/10/21 19:45 | Queens Park Rangers | Nottingham Forest | 1-1 | 4 - 6 - 6 |
| 30/10/21 12:30 | 30/10/21 12:30 | Fulham FC | West Bromwich Albion | 3-0 | 4 - 4 - 10 |
| 30/10/21 15:00 | 30/10/21 15:00 | Bristol City | Barnsley FC | 2-1 | 3 - 9 - 10 |
| 30/10/21 15:00 | 30/10/21 15:00 | Derby County | Blackburn Rovers | 1-2 | 4 - 5 - 7 |
| 30/10/21 15:00 | 30/10/21 15:00 | Stoke City | Cardiff City | 3-3 | 3 - 9 - 10 |
| 30/10/21 15:00 | 30/10/21 15:00 | Swansea City | Peterborough United | 3-0 | 4 - 7 - 9 |
| 30/10/21 15:00 | 30/10/21 15:00 | Huddersfield Town | Millwall FC | 1-0 | 5 - 5 - 6 |
| 30/10/21 15:00 | 30/10/21 15:00 | Hull City A.F.C. | Coventry City | 0-1 | 5 - 6 - 5 |
| 30/10/21 15:00 | 30/10/21 15:00 | Middlesbrough FC | Birmingham City | 0-2 | 4 - 6 - 7 |
| 30/10/21 15:00 | 30/10/21 15:00 | Preston North End | Luton Town | 2-0 | 5 - 6 - 4 |
| 30/10/21 15:00 | 30/10/21 15:00 | Sheffield United | FC Blackpool | 0-1 | 3 - 10 - 9 |
| 30/10/21 20:00 | 30/10/21 20:00 | Reading FC | AFC Bournemouth | 0-2 | 7 - 9 - 4 |