Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 28/01/27 20:00 | 28/01/27 20:00 | 1899 Hoffenheim | Ferencvaros Budapest | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Omonia Nicosia | Besiktas Istanbul | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | NK Celje | NEC Nijmwegen | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | AFC Bournemouth | Hapoel Beer Sheva | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Viktoria Plzen | Jagiellonia Bialystok | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Royale Union Saint-Gilloise | Celtic Glasgow | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Olympique Marseille | RSC Anderlecht | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Olympique Lyon | Bayer 04 Leverkusen | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Sparta Prag | Stade Rennes | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | FC Red Bull Salzburg | Crystal Palace | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Dinamo Zagreb | SK Sturm Graz | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Juventus Turin | Real Sociedad | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Benfica Lisbon | AZ Alkmaar | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | AC Milan | FC Ararat-Armenia | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | OFI Crete | Lech Poznan | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | Celta Vigo | Lillestroem SK | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | AFC Sunderland | Levski Sofia | --- | 2 - 4 points |
| 28/01/27 20:00 | 28/01/27 20:00 | SCU Torreense | Olympiakos Piräus | --- | 2 - 4 points |