Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 16/09/26 17:45 | 16/09/26 17:45 | FC Ararat-Armenia | Sparta Prag | --- | 2 - 4 points |
| 16/09/26 17:45 | 16/09/26 17:45 | Omonia Nicosia | Celta Vigo | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | Bayer 04 Leverkusen | NK Celje | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | AC Milan | Benfica Lisbon | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | Hapoel Beer Sheva | Dinamo Zagreb | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | Olympiakos Piräus | Jagiellonia Bialystok | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | RSC Anderlecht | Olympique Lyon | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | SK Sturm Graz | Stade Rennes | --- | 2 - 4 points |
| 16/09/26 20:00 | 16/09/26 20:00 | AFC Sunderland | AZ Alkmaar | --- | 2 - 4 points |
| 17/09/26 17:45 | 17/09/26 17:45 | OFI Crete | 1899 Hoffenheim | --- | 2 - 4 points |
| 17/09/26 17:45 | 17/09/26 17:45 | Levski Sofia | FC Red Bull Salzburg | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Besiktas Istanbul | Olympique Marseille | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Celtic Glasgow | Ferencvaros Budapest | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Crystal Palace | Lech Poznan | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Viktoria Plzen | Royale Union Saint-Gilloise | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Juventus Turin | NEC Nijmwegen | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Lillestroem SK | SCU Torreense | --- | 2 - 4 points |
| 17/09/26 20:00 | 17/09/26 20:00 | Real Sociedad | AFC Bournemouth | --- | 2 - 4 points |