Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 27/11/25 17:45 | 27/11/25 17:45 | PAOK Saloniki | Brann Bergen | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | PFC Ludogorets Razgrad | Celta Vigo | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | Feyenoord Rotterdam | Celtic Glasgow | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | OSC Lille | Dinamo Zagreb | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | Aston Villa | Young Boys Bern | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | FC Porto | OGC Nice | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | Fenerbahce Istanbul | Ferencvaros Budapest | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | Viktoria Plzen | SC Freiburg | --- | 2 - 4 points |
| 27/11/25 17:45 | 27/11/25 17:45 | AS Roma | FC Midtjylland | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | KRC Genk | FC Basel | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Nottingham Forest | Malmö FF | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Go Ahead Eagles Deventer | VfB Stuttgart | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Panathinaikos Athens | SK Sturm Graz | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | FC Bologna | FC Red Bull Salzburg | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Maccabi Tel Aviv | Olympique Lyon | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Red Star Belgrad | FCSB Bukarest | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Glasgow Rangers | Sporting Braga | --- | 2 - 4 points |
| 27/11/25 20:00 | 27/11/25 20:00 | Real Betis Sevilla | FC Utrecht | --- | 2 - 4 points |