Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 06/11/25 17:45 | 06/11/25 17:45 | FC Utrecht | FC Porto | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | FC Red Bull Salzburg | Go Ahead Eagles Deventer | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | Red Star Belgrad | OSC Lille | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | SK Sturm Graz | Nottingham Forest | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | FC Midtjylland | Celtic Glasgow | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | FC Basel | FCSB Bukarest | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | Dinamo Zagreb | Celta Vigo | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | Malmö FF | Panathinaikos Athens | --- | 2 - 4 points |
| 06/11/25 17:45 | 06/11/25 17:45 | OGC Nice | SC Freiburg | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | FC Bologna | Brann Bergen | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | Sporting Braga | KRC Genk | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | PAOK Saloniki | Young Boys Bern | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | Aston Villa | Maccabi Tel Aviv | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | VfB Stuttgart | Feyenoord Rotterdam | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | Ferencvaros Budapest | PFC Ludogorets Razgrad | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | Glasgow Rangers | AS Roma | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | Real Betis Sevilla | Olympique Lyon | --- | 2 - 4 points |
| 06/11/25 20:00 | 06/11/25 20:00 | Viktoria Plzen | Fenerbahce Istanbul | --- | 2 - 4 points |