| Date | Home | Away | Result |
|---|---|---|---|
| 26/08/22 19:30 | SC Freiburg | VfL Bochum | 1-0 |
| 27/08/22 14:30 | Hertha BSC | Borussia Dortmund | 0-1 |
| 27/08/22 14:30 | 1899 Hoffenheim | FC Augsburg | 1-0 |
| 27/08/22 14:30 | FC Schalke 04 | 1. FC Union Berlin | 1-6 |
| 27/08/22 14:30 | RB Leipzig | VfL Wolfsburg | 2-0 |
| 27/08/22 14:30 | FSV Mainz 05 | Bayer 04 Leverkusen | 0-3 |
| 27/08/22 17:30 | FC Bayern Munich | Bor. Mönchengladbach | 1-1 |
| 28/08/22 14:30 | 1. FC Köln | VfB Stuttgart | 0-0 |
| 28/08/22 16:30 | Werder Bremen | Eintracht Frankfurt | 3-4 |