| Date | Home | Away | Result |
|---|---|---|---|
| 19/08/22 19:30 | Bor. Mönchengladbach | Hertha BSC | 1-0 |
| 20/08/22 14:30 | FC Augsburg | FSV Mainz 05 | 1-2 |
| 20/08/22 14:30 | Borussia Dortmund | Werder Bremen | 2-3 |
| 20/08/22 14:30 | VfL Wolfsburg | FC Schalke 04 | 0-0 |
| 20/08/22 14:30 | VfB Stuttgart | SC Freiburg | 0-1 |
| 20/08/22 14:30 | Bayer 04 Leverkusen | 1899 Hoffenheim | 0-3 |
| 20/08/22 17:30 | 1. FC Union Berlin | RB Leipzig | 2-1 |
| 21/08/22 14:30 | Eintracht Frankfurt | 1. FC Köln | 1-1 |
| 21/08/22 16:30 | VfL Bochum | FC Bayern Munich | 0-7 |