| Date | Home | Away | Result |
|---|---|---|---|
| 05/08/22 19:35 | Eintracht Frankfurt | FC Bayern Munich | 1-6 |
| 06/08/22 14:30 | FC Augsburg | SC Freiburg | 0-4 |
| 06/08/22 14:30 | VfL Bochum | FSV Mainz 05 | 1-2 |
| 06/08/22 14:30 | Bor. Mönchengladbach | 1899 Hoffenheim | 3-1 |
| 06/08/22 14:30 | 1. FC Union Berlin | Hertha BSC | 3-1 |
| 06/08/22 14:30 | VfL Wolfsburg | Werder Bremen | 2-2 |
| 06/08/22 17:30 | Borussia Dortmund | Bayer 04 Leverkusen | 1-0 |
| 07/08/22 14:30 | VfB Stuttgart | RB Leipzig | 1-1 |
| 07/08/22 16:30 | 1. FC Köln | FC Schalke 04 | 3-1 |