| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 14/11/21 14:00 | Malta | Slovakia | Group H | 0-6 |
| 14/11/21 14:00 | Slovenia | Cyprus | Group H | 2-1 |
| 14/11/21 14:00 | Croatia | Russia | Group H | 1-0 |
| 14/11/21 17:00 | North Macedonia | Iceland | Group J | 3-1 |
| 14/11/21 17:00 | Armenia | Germany | Group J | 1-4 |
| 14/11/21 17:00 | Liechtenstein | Romania | Group J | 0-2 |
| 14/11/21 19:45 | Greece | Kosovo | Group B | 1-1 |
| 14/11/21 19:45 | Portugal | Serbia | Group A | 1-2 |
| 14/11/21 19:45 | Luxembourg | Ireland | Group A | 0-3 |
| 14/11/21 19:45 | Spain | Sweden | Group B | 1-0 |
| 15/11/21 19:45 | Switzerland | Bulgaria | Group C | 4-0 |
| 15/11/21 19:45 | San Marino | England | Group I | 0-10 |
| 15/11/21 19:45 | Poland | Hungary | Group I | 1-2 |
| 15/11/21 19:45 | Israel | Faroe Islands | Group F | 3-2 |
| 15/11/21 19:45 | Albania | Andorra | Group I | 1-0 |
| 15/11/21 19:45 | Northern Ireland | Italy | Group C | 0-0 |
| 15/11/21 19:45 | Scotland | Denmark | Group F | 2-0 |
| 15/11/21 19:45 | Austria | Moldova | Group F | 4-1 |
| 16/11/21 19:45 | Netherlands | Norway | Group G | 2-0 |
| 16/11/21 19:45 | Gibraltar | Latvia | Group G | 1-3 |
| 16/11/21 19:45 | Czech Republic | Estonia | Group E | 2-0 |
| 16/11/21 19:45 | Finlande | France | Group D | 0-2 |
| 16/11/21 19:45 | Montenegro | Turkey | Group G | 1-2 |
| 16/11/21 19:45 | Bosnien-Herzegowina | Ukraine | Group D | 0-2 |
| 16/11/21 19:45 | Wales | Belgium | Group E | 1-1 |