| Date | Home | Away | Result |
|---|---|---|---|
| 12/09/25 19:30 | UD Las Palmas | Real Sociedad B | 2-1 |
| 13/09/25 15:15 | CD Mirandes | Deportivo La Coruna | 1-5 |
| 13/09/25 15:15 | FC Cadiz | SD Eibar | 1-0 |
| 13/09/25 17:30 | SD Huesca | FC Malaga | 1-0 |
| 13/09/25 20:00 | Real Valladolid | UD Almeria | 3-1 |
| 14/09/25 13:00 | Andorra CF | Cordoba CF | 3-1 |
| 14/09/25 15:15 | Racing Santander | CyD Leonesa | 2-4 |
| 14/09/25 17:30 | Sporting Gijon | Burgos CF | 2-3 |
| 14/09/25 17:30 | CD Castellon | AD Ceuta FC | 3-3 |
| 14/09/25 20:00 | FC Granada | CD Leganes | 0-2 |
| 15/09/25 19:30 | Real Saragossa | Albacete Balompie | 0-0 |