| Date | Home | Away | Result |
|---|---|---|---|
| 24/10/25 19:45 | Sporting Charleroi | RSC Anderlecht | 1-0 |
| 25/10/25 15:00 | KVC Westerlo | FCV Dender EH | 1-1 |
| 25/10/25 17:15 | KV Mechelen | OH Leuven | 1-1 |
| 25/10/25 19:45 | KAA Gent | Standard Liège | 4-0 |
| 26/10/25 12:30 | Royal Antwerp FC | Club Brugge | 0-1 |
| 26/10/25 15:00 | KSV Cercle Brügge | SV Zulte-Waregem | 1-1 |
| 26/10/25 17:30 | KRC Genk | RAAL La Louviere | 1-1 |
| 26/10/25 18:15 | Royale Union Saint-Gilloise | Sint-Truidense VV | 2-0 |