| Date | Home | Away | Result |
|---|---|---|---|
| 21/10/22 00:00 | Columbus Blue Jackets | Nashville Predators | 5-3 |
| 21/10/22 00:00 | Toronto Maple Leafs | Dallas Stars | 3-2OT |
| 21/10/22 00:00 | Pittsburgh Penguins | Los Angeles Kings | 6-1 |
| 21/10/22 00:00 | Ottawa Senators | Washington Capitals | 5-2 |
| 21/10/22 00:00 | New York Rangers | San Jose Sharks | 2-3OT |
| 21/10/22 00:00 | Montréal Canadiens | Arizona Coyotes | 6-2 |
| 21/10/22 00:00 | Boston Bruins | Anaheim Ducks | 2-1a.pen. |
| 21/10/22 00:30 | New York Islanders | New Jersey Devils | 1-4 |
| 21/10/22 01:00 | Minnesota Wild | Vancouver Canucks | 4-3OT |
| 21/10/22 02:00 | Edmonton Oilers | Carolina Hurricanes | 6-4 |
| 21/10/22 02:30 | Calgary Flames | Buffalo Sabres | 3-6 |
| 21/10/22 03:00 | Vegas Golden Knights | Winnipeg Jets | 5-2 |