| Date | Home | Away | Result |
|---|---|---|---|
| 30/09/22 01:15 | Cincinnati Bengals | Miami Dolphins | 27-15 |
| 02/10/22 14:30 | New Orleans Saints | Minnesota Vikings | 25-28 |
| 02/10/22 18:00 | Houston Texans | Los Angeles Chargers | 24-34 |
| 02/10/22 18:00 | Indianapolis Colts | Tennessee Titans | 17-24 |
| 02/10/22 18:00 | Detroit Lions | Seattle Seahawks | 45-48 |
| 02/10/22 18:00 | Baltimore Ravens | Buffalo Bills | 20-23 |
| 02/10/22 18:00 | Dallas Cowboys | Washington Commanders | 25-10 |
| 02/10/22 18:00 | Atlanta Falcons | Cleveland Browns | 23-20 |
| 02/10/22 18:00 | New York Giants | Chicago Bears | 20-12 |
| 02/10/22 18:00 | Pittsburgh Steelers | New York Jets | 20-24 |
| 02/10/22 18:00 | Philadelphia Eagles | Jacksonville Jaguars | 29-21 |
| 02/10/22 21:05 | Carolina Panthers | Arizona Cardinals | 16-26 |
| 02/10/22 21:25 | Las Vegas Raiders | Denver Broncos | 32-23 |
| 02/10/22 21:25 | Green Bay Packers | New England Patriots | 27-24OT |
| 03/10/22 01:20 | Tampa Bay Buccaneers | Kansas City Chiefs | 31-41 |
| 04/10/22 01:15 | San Francisco 49ers | Los Angeles Rams | 24-9 |