| Eastern Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Inter Miami CF | 18 | 35 | 42 | 27 | 15 | 10 | 5 | 3 |
| 2. | Cincinnati FC | 16 | 33 | 23 | 16 | 7 | 10 | 3 | 3 |
| 3. | New York Red Bulls | 16 | 29 | 29 | 22 | 7 | 8 | 5 | 3 |
| 4. | New York City FC | 16 | 29 | 24 | 17 | 7 | 9 | 2 | 5 |
| 5. | Columbus Crew | 14 | 24 | 21 | 13 | 8 | 6 | 6 | 2 |
| 6. | Toronto FC | 17 | 24 | 26 | 26 | 0 | 7 | 3 | 7 |
| 7. | Charlotte FC | 16 | 22 | 15 | 16 | -1 | 6 | 4 | 6 |
| 8. | Philadelphia Union | 16 | 20 | 27 | 23 | 4 | 4 | 8 | 4 |
| 9. | Nashville SC | 16 | 19 | 20 | 22 | -2 | 4 | 7 | 5 |
| 10. | D.C. United | 17 | 19 | 25 | 31 | -6 | 4 | 7 | 6 |
| 11. | Orlando City | 16 | 17 | 16 | 24 | -8 | 4 | 5 | 7 |
| 12. | CF Montreal | 16 | 17 | 23 | 35 | -12 | 4 | 5 | 7 |
| 13. | Atlanta United FC | 15 | 16 | 20 | 18 | 2 | 4 | 4 | 7 |
| 14. | Chicago Fire | 17 | 15 | 17 | 29 | -12 | 3 | 6 | 8 |
| 15. | New England Revolution | 14 | 10 | 11 | 27 | -16 | 3 | 1 | 10 |
| Western Conference | P | Pts | GF | GA | GD | w | d | l | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Real Salt Lake | 17 | 33 | 35 | 18 | 17 | 9 | 6 | 2 |
| 2. | Los Angeles FC | 16 | 28 | 27 | 19 | 8 | 8 | 4 | 4 |
| 3. | Minnesota United FC | 15 | 28 | 27 | 20 | 7 | 8 | 4 | 3 |
| 4. | Los Angeles Galaxy | 17 | 28 | 31 | 25 | 6 | 7 | 7 | 3 |
| 5. | Vancouver Whitecaps | 16 | 23 | 22 | 18 | 4 | 6 | 5 | 5 |
| 6. | Colorado Rapids | 17 | 23 | 28 | 29 | -1 | 6 | 5 | 6 |
| 7. | Austin FC | 17 | 23 | 20 | 24 | -4 | 6 | 5 | 6 |
| 8. | Houston Dynamo | 16 | 22 | 16 | 16 | 0 | 6 | 4 | 6 |
| 9. | Portland Timbers | 17 | 20 | 30 | 30 | 0 | 5 | 5 | 7 |
| 10. | Seattle Sounders | 16 | 18 | 19 | 19 | 0 | 4 | 6 | 6 |
| 11. | St. Louis City SC | 15 | 17 | 23 | 25 | -2 | 3 | 8 | 4 |
| 12. | FC Dallas | 15 | 14 | 17 | 23 | -6 | 3 | 5 | 7 |
| 13. | Sporting Kansas City | 16 | 11 | 24 | 31 | -7 | 2 | 5 | 9 |
| 14. | San Jose Earthquakes | 16 | 11 | 24 | 39 | -15 | 3 | 2 | 11 |