| Date | Home | Away | Result |
|---|---|---|---|
| 19/10/24 23:00 | Orlando City | Atlanta United FC | --- |
| 19/10/24 23:00 | Inter Miami CF | New England Revolution | --- |
| 19/10/24 23:00 | Chicago Fire | Nashville SC | --- |
| 19/10/24 23:00 | Philadelphia Union | Cincinnati FC | --- |
| 19/10/24 23:00 | New York Red Bulls | Columbus Crew | --- |
| 19/10/24 23:00 | D.C. United | Charlotte FC | --- |
| 19/10/24 23:00 | CF Montreal | New York City FC | --- |
| 20/10/24 02:00 | Seattle Sounders | Portland Timbers | --- |
| 20/10/24 02:00 | Austin FC | Colorado Rapids | --- |
| 20/10/24 02:00 | Real Salt Lake | Vancouver Whitecaps | --- |
| 20/10/24 02:00 | Houston Dynamo | Los Angeles Galaxy | --- |
| 20/10/24 02:00 | Los Angeles FC | San Jose Earthquakes | --- |
| 20/10/24 02:00 | Minnesota United FC | St. Louis City SC | --- |
| 20/10/24 02:00 | FC Dallas | Sporting Kansas City | --- |