| Date | Home | Away | Result |
|---|---|---|---|
| 12/05/24 00:30 | Toronto FC | New York City FC | 2-3 |
| 12/05/24 00:30 | Philadelphia Union | Orlando City | 2-3 |
| 12/05/24 00:30 | CF Montreal | Inter Miami CF | 2-3 |
| 12/05/24 00:30 | Atlanta United FC | D.C. United | 2-3 |
| 12/05/24 00:30 | Charlotte FC | Nashville SC | 1-0 |
| 12/05/24 00:30 | New York Red Bulls | New England Revolution | 4-2 |
| 12/05/24 00:45 | Columbus Crew | Cincinnati FC | 1-2 |
| 12/05/24 01:30 | St. Louis City SC | Chicago Fire | 3-1 |
| 12/05/24 01:30 | Sporting Kansas City | Houston Dynamo | 1-2 |
| 12/05/24 01:30 | FC Dallas | Austin FC | 2-1 |
| 12/05/24 02:30 | Colorado Rapids | San Jose Earthquakes | 2-3 |
| 12/05/24 03:30 | Los Angeles FC | Vancouver Whitecaps | 3-0 |
| 12/05/24 03:30 | Los Angeles Galaxy | Real Salt Lake | 2-2 |
| 12/05/24 21:45 | Portland Timbers | Seattle Sounders | 1-2 |