| Date | Home | Away | Result |
|---|---|---|---|
| 02/07/23 00:30 | Orlando City | Chicago Fire | 3-1 |
| 02/07/23 00:30 | Columbus Crew | New York Red Bulls | 2-1 |
| 02/07/23 00:30 | Inter Miami CF | Austin FC | 1-1 |
| 02/07/23 00:30 | Cincinnati FC | New England Revolution | 2-2 |
| 02/07/23 00:30 | Toronto FC | Real Salt Lake | 0-1 |
| 02/07/23 00:30 | CF Montreal | New York City FC | 0-1 |
| 02/07/23 01:30 | St. Louis City SC | Colorado Rapids | 2-0 |
| 02/07/23 01:30 | Minnesota United FC | Portland Timbers | 4-1 |
| 02/07/23 01:30 | Nashville SC | D.C. United | 2-0 |
| 02/07/23 01:30 | FC Dallas | Los Angeles FC | 2-0 |
| 02/07/23 01:30 | Sporting Kansas City | Vancouver Whitecaps | 3-0 |
| 02/07/23 03:30 | Seattle Sounders | Houston Dynamo | 1-0 |
| 02/07/23 03:30 | San Jose Earthquakes | Los Angeles Galaxy | 2-2 |
| 02/07/23 21:00 | Atlanta United FC | Philadelphia Union | 2-0 |