| Date | Home | Away | Result |
|---|---|---|---|
| 04/03/23 21:30 | Los Angeles FC | Portland Timbers | 3-2 |
| 05/03/23 00:30 | Atlanta United FC | Toronto FC | 1-1 |
| 05/03/23 00:30 | New York Red Bulls | Nashville SC | 0-0 |
| 05/03/23 00:30 | Orlando City | Cincinnati FC | 0-0 |
| 05/03/23 00:30 | Inter Miami CF | Philadelphia Union | 2-0 |
| 05/03/23 00:30 | New England Revolution | Houston Dynamo | 3-0 |
| 05/03/23 00:30 | Columbus Crew | D.C. United | 2-0 |
| 05/03/23 01:30 | Austin FC | CF Montreal | 1-0 |
| 05/03/23 01:30 | St. Louis City SC | Charlotte FC | 3-1 |
| 05/03/23 01:30 | Chicago Fire | New York City FC | 1-1 |
| 05/03/23 01:30 | FC Dallas | Los Angeles Galaxy | 3-1 |
| 05/03/23 02:30 | Colorado Rapids | Sporting Kansas City | 0-0 |
| 05/03/23 03:30 | San Jose Earthquakes | Vancouver Whitecaps | 2-1 |
| 05/03/23 03:30 | Seattle Sounders | Real Salt Lake | 2-0 |