| Date | Home | Away | Result |
|---|---|---|---|
| 17/10/26 19:30 | Philadelphia Union | Charlotte FC | 2-2 |
| 17/10/26 21:30 | Minnesota United FC | St. Louis City SC | 0-2 |
| 18/10/26 00:30 | Orlando City | D.C. United | --- |
| 18/10/26 00:30 | New England Revolution | Chicago Fire | --- |
| 18/10/26 00:30 | New York Red Bulls | Toronto FC | --- |
| 18/10/26 00:30 | Atlanta United FC | Inter Miami CF | --- |
| 18/10/26 00:30 | New York City FC | Los Angeles FC | --- |
| 18/10/26 01:30 | Houston Dynamo | FC Dallas | --- |
| 18/10/26 01:30 | Austin FC | Vancouver Whitecaps | --- |
| 18/10/26 01:30 | Sporting Kansas City | Real Salt Lake | --- |
| 18/10/26 03:30 | Seattle Sounders | CF Montreal | --- |
| 18/10/26 03:30 | Los Angeles Galaxy | San Diego FC | --- |
| 18/10/26 03:30 | Portland Timbers | Colorado Rapids | --- |
| 18/10/26 03:30 | San Jose Earthquakes | Nashville SC | --- |
| 18/10/26 22:00 | Cincinnati FC | Columbus Crew | --- |