| Date | Home | Away | Result |
|---|---|---|---|
| 27/01/23 20:00 | Manchester City | Arsenal FC | 1-0 |
| 28/01/23 12:30 | FC Walsall | Leicester City | 0-1 |
| 28/01/23 12:30 | Accrington Stanley | Leeds United | 1-3 |
| 28/01/23 15:00 | Fulham FC | AFC Sunderland | 1-1 |
| 28/01/23 15:00 | Sheffield Wednesday | Fleetwood Town | 1-1 |
| 28/01/23 15:00 | Ipswich Town | Burnley FC | 0-0 |
| 28/01/23 15:00 | Southampton FC | FC Blackpool | 2-1 |
| 28/01/23 15:00 | Luton Town | Grimsby Town | 2-2 |
| 28/01/23 15:00 | Bristol City | West Bromwich Albion | 3-0 |
| 28/01/23 15:00 | Blackburn Rovers | Birmingham City | 2-2 |
| 28/01/23 18:00 | Preston North End | Tottenham Hotspur | 0-3 |
| 28/01/23 20:00 | Manchester United | Reading FC | 3-1 |
| 29/01/23 13:30 | Brighton and Hove Albion | Liverpool FC | 2-1 |
| 29/01/23 14:00 | Stoke City | Stevenage FC | 3-1 |
| 29/01/23 16:30 | AFC Wrexham | Sheffield United | 3-3 |
| 30/01/23 19:45 | Derby County | West Ham United | 0-2 |
| 31/01/23 19:45 | Birmingham City | Blackburn Rovers | 0-1a.e.t |
| 07/02/23 19:45 | Grimsby Town | Luton Town | 3-0 |
| 07/02/23 19:45 | Burnley FC | Ipswich Town | 2-1 |
| 07/02/23 19:45 | Fleetwood Town | Sheffield Wednesday | 1-0 |
| 07/02/23 19:45 | Sheffield United | AFC Wrexham | 3-1 |
| 08/02/23 19:45 | AFC Sunderland | Fulham FC | 2-3 |