| Date | Home | Away | Result |
|---|---|---|---|
| 22/02/24 17:45 | SC Freiburg | RC Lens | 3-2a.e.t |
| 22/02/24 17:45 | Qarabag | Sporting Braga | 2-3a.e.t |
| 22/02/24 17:45 | FC Toulouse | Benfica Lisbon | 0-0 |
| 22/02/24 17:45 | Stade Rennes | AC Milan | 3-2 |
| 22/02/24 20:00 | Sporting Lisbon | Young Boys Bern | 1-1 |
| 22/02/24 20:00 | Olympique Marseille | Schachtjor Donezk | 3-1 |
| 22/02/24 20:00 | Sparta Prag | Galatasaray Istanbul | 4-1 |
| 22/02/24 20:00 | AS Roma | Feyenoord Rotterdam | 5-3a.PSO |