| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 23/04/24 23:00 | Caracas FC | Rosario Central | Group G | 1-1 |
| 23/04/24 23:00 | Estudiantes de La Plata | Gremio Porto Alegre | Group C | 0-1 |
| 24/04/24 01:00 | Club Atletico Mineiro | Club Atlético Peñarol | Group G | 3-2 |
| 24/04/24 01:00 | Liverpool F.C. | CA San Lorenzo | Group F | 1-0 |
| 24/04/24 01:30 | Colo-Colo | Alianza Lima | Group A | 0-0 |
| 24/04/24 03:00 | Junior FC | LDU Quito | Group D | 1-1 |
| 24/04/24 23:00 | Club Nacional de Football | Deportivo Tachira | Group H | 2-1 |
| 24/04/24 23:00 | Botafogo | Universitario | Group D | 3-1 |
| 24/04/24 23:00 | Huachipato | The Strongest | Group C | 0-0 |
| 25/04/24 01:30 | Club Libertad | River Plate | Group H | 1-2 |
| 25/04/24 01:30 | Independiente del Valle | Palmeiras | Group F | 2-3 |
| 25/04/24 01:30 | Club Bolívar | Flamengo | Group E | 2-1 |
| 25/04/24 23:00 | Cobresal | CA Talleres | Group B | 0-2 |
| 25/04/24 23:00 | Club Cerro Porteno | Fluminense | Group A | 0-0 |
| 26/04/24 01:00 | Palestino | Millonarios FC | Group E | 3-1 |
| 26/04/24 01:00 | Barcelona SC | FC Sao Paulo | Group B | 0-2 |