| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 02/04/24 23:00 | Millonarios FC | Flamengo | Group E | 1-1 |
| 02/04/24 23:00 | Cobresal | Barcelona SC | Group B | 1-1 |
| 03/04/24 01:00 | The Strongest | Gremio Porto Alegre | Group C | 2-0 |
| 03/04/24 01:30 | Deportivo Tachira | River Plate | Group H | 0-2 |
| 03/04/24 03:00 | Universitario | LDU Quito | Group D | 2-1 |
| 03/04/24 23:00 | Club Nacional de Football | Club Libertad | Group H | 2-0 |
| 03/04/24 23:00 | Botafogo | Junior FC | Group D | 1-3 |
| 03/04/24 23:00 | Huachipato | Estudiantes de La Plata | Group C | 1-1 |
| 04/04/24 01:00 | Colo-Colo | Club Cerro Porteno | Group A | 1-0 |
| 04/04/24 01:30 | CA San Lorenzo | Palmeiras | Group F | 1-1 |
| 04/04/24 01:30 | Alianza Lima | Fluminense | Group A | 1-1 |
| 04/04/24 23:00 | Rosario Central | Club Atlético Peñarol | Group G | 1-0 |
| 04/04/24 23:00 | Caracas FC | Club Atletico Mineiro | Group G | 1-4 |
| 05/04/24 01:00 | Liverpool F.C. | Independiente del Valle | Group F | 1-1 |
| 05/04/24 01:00 | Palestino | Club Bolívar | Group E | 0-4 |
| 05/04/24 01:00 | CA Talleres | FC Sao Paulo | Group B | 2-1 |