| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 18/04/23 23:00 | Fluminense | The Strongest | Group D | 1-0 |
| 18/04/23 23:00 | Internacional | Metropolitanos FC | Group B | 1-0 |
| 19/04/23 01:00 | Athletico Paranaense | Club Atletico Mineiro | Group G | 2-1 |
| 19/04/23 01:00 | Club Olimpia | CA Patronato Parana | Group H | 1-0 |
| 19/04/23 01:00 | Boca Juniors | Deportivo Pereira | Group F | 2-1 |
| 19/04/23 03:00 | Independiente del Valle | Liverpool F.C. | Group E | 2-0 |
| 19/04/23 23:00 | Club Nacional de Football | Independiente Medellín | Group B | 2-1 |
| 20/04/23 01:00 | River Plate | Sporting Cristal | Group D | 4-2 |
| 20/04/23 01:30 | Flamengo | Ñublense | Group A | 2-0 |
| 20/04/23 01:30 | Corinthians | Argentinos Juniors | Group E | 0-1 |
| 20/04/23 02:00 | Colo-Colo | Monagas SC | Group F | 1-0 |
| 20/04/23 03:00 | Barcelona SC | Club Bolívar | Group C | 2-1 |
| 20/04/23 23:00 | Racing Club | SD Aucas | Group A | 3-2 |
| 21/04/23 01:00 | Palmeiras | Club Cerro Porteno | Group C | 2-1 |
| 21/04/23 01:00 | Atlético Nacional | FBC Melgar | Group H | 3-1 |
| 21/04/23 03:00 | Club Libertad | Alianza Lima | Group G | 1-2 |