| Date | Home | Away | Group | Result |
|---|---|---|---|---|
| 05/10/23 15:30 | FK Astana | Viktoria Plzen | Group C | 1-2 |
| 05/10/23 17:45 | Besiktas Istanbul | FC Lugano | Group D | 2-3 |
| 05/10/23 17:45 | FK Bodö/Glimt | Club Brugge | Group D | 0-1 |
| 05/10/23 17:45 | KF Ballkani Suhareka | Dinamo Zagreb | Group C | 2-0 |
| 05/10/23 17:45 | KAA Gent | Maccabi Tel Aviv | Group B | 2-0 |
| 05/10/23 17:45 | Breidablik Kopavogur | FC Zorya Lugansk | Group B | 0-1 |
| 05/10/23 17:45 | KÍ Klaksvík | OSC Lille | Group A | 0-0 |
| 05/10/23 17:45 | Olimpija Ljubljana | SK Slovan Bratislava | Group A | 0-1 |
| 05/10/23 20:00 | Fiorentina | Ferencvaros Budapest | Group F | 2-2 |
| 05/10/23 20:00 | FK Čukarički | KRC Genk | Group F | 0-2 |
| 05/10/23 20:00 | FC Nordsjaelland | PFC Ludogorets Razgrad | Group H | 7-1 |
| 05/10/23 20:00 | Spartak Trnava | Fenerbahce Istanbul | Group H | 1-2 |
| 05/10/23 20:00 | PAOK Saloniki | Eintracht Frankfurt | Group G | 2-1 |
| 05/10/23 20:00 | FC Aberdeen | HJK Helsinki | Group G | 1-1 |
| 05/10/23 20:00 | Aston Villa | HŠK Zrinjski Mostar | Group E | 1-0 |
| 05/10/23 20:00 | AZ Alkmaar | Legia Warschau | Group E | 1-0 |