| Date | Home | Away | Result |
|---|---|---|---|
| 20/10/26 17:45 | Fenerbahce Istanbul | Slavia Prag | 2-2 |
| 20/10/26 17:45 | Sabah FK | Borussia Dortmund | 1-2 |
| 20/10/26 20:00 | AS Roma | SK Slovan Bratislava | 4-0 |
| 20/10/26 20:00 | Liverpool FC | FC Villarreal | 4-3 |
| 20/10/26 20:00 | FC Porto | PSV Eindhoven | 0-1 |
| 20/10/26 20:00 | SSC Napoli | FK Bodö/Glimt | 4-3 |
| 20/10/26 20:00 | Manchester City | AEK Athens | 5-1 |
| 20/10/26 20:00 | Paris St. Germain | FC Barcelona | 4-2 |
| 20/10/26 20:00 | VfB Stuttgart | Atletico Madrid | 1-1 |
| 21/10/26 17:45 | Como Calcio | Manchester United | 4-1 |
| 21/10/26 17:45 | OSC Lille | Galatasaray Istanbul | 2-4 |
| 21/10/26 20:00 | Aston Villa | Viking Stavanger | 3-1 |
| 21/10/26 20:00 | Club Brugge | RC Lens | 3-0 |
| 21/10/26 20:00 | FC Bayern Munich | Arsenal FC | 2-2 |
| 21/10/26 20:00 | Real Betis Sevilla | Feyenoord Rotterdam | 1-0 |
| 21/10/26 20:00 | Inter Milan | Schachtjor Donezk | 1-0 |
| 21/10/26 20:00 | Real Madrid | RB Leipzig | 4-1 |
| 21/10/26 20:00 | Sporting Lisbon | Linzer ASK | 2-3 |