| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 19/08/22 17:30 | 19/08/22 17:15 | 1. FC Magdeburg | Hannover 96 | 0-4 | 2 - 4 points |
| 19/08/22 17:30 | 19/08/22 17:15 | Hamburger SV | SV Darmstadt 98 | 1-2 | 2 - 4 points |
| 20/08/22 12:00 | 20/08/22 11:45 | SV Sandhausen | 1. FC Nürnberg | 1-2 | 2 - 4 points |
| 20/08/22 12:00 | 20/08/22 11:45 | SC Paderborn 07 | Holstein Kiel | 7-2 | 2 - 4 points |
| 20/08/22 12:00 | 20/08/22 11:45 | Jahn Regensburg | Karlsruher SC | 0-6 | 2 - 4 points |
| 20/08/22 19:30 | 20/08/22 19:15 | Eintracht Braunschweig | Fortuna Düsseldorf | 2-2 | 2 - 4 points |
| 21/08/22 12:30 | 21/08/22 12:15 | SpVgg Greuther Fürth | 1. FC Kaiserslautern | 1-3 | 2 - 4 points |
| 21/08/22 12:30 | 21/08/22 12:15 | 1. FC Heidenheim 1846 | Arminia Bielefeld | 1-1 | 2 - 4 points |
| 21/08/22 12:30 | 21/08/22 12:15 | FC Hansa Rostock | FC St. Pauli | 2-0 | 2 - 4 points |