| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 05/08/22 17:30 | 05/08/22 17:15 | SV Sandhausen | Fortuna Düsseldorf | 1-0 | 2 - 4 points |
| 05/08/22 17:30 | 05/08/22 17:15 | SpVgg Greuther Fürth | Karlsruher SC | 1-1 | 2 - 4 points |
| 06/08/22 12:00 | 06/08/22 11:45 | SC Paderborn 07 | Hannover 96 | 4-2 | 2 - 4 points |
| 06/08/22 12:00 | 06/08/22 11:45 | Hamburger SV | 1. FC Heidenheim 1846 | 1-0 | 2 - 4 points |
| 06/08/22 12:00 | 06/08/22 11:45 | Jahn Regensburg | 1. FC Nürnberg | 0-0 | 2 - 4 points |
| 06/08/22 19:30 | 06/08/22 19:15 | FC Hansa Rostock | Arminia Bielefeld | 2-1 | 2 - 4 points |
| 07/08/22 12:30 | 07/08/22 12:15 | 1. FC Kaiserslautern | FC St. Pauli | 2-1 | 2 - 4 points |
| 07/08/22 12:30 | 07/08/22 12:15 | Eintracht Braunschweig | SV Darmstadt 98 | 0-1 | 2 - 4 points |
| 07/08/22 12:30 | 07/08/22 12:15 | 1. FC Magdeburg | Holstein Kiel | 1-2 | 2 - 4 points |