| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 04/11/22 17:30 | 04/11/22 17:15 | SV Darmstadt 98 | Hannover 96 | 1-0 | 2 - 4 points |
| 04/11/22 17:30 | 04/11/22 17:15 | FC Hansa Rostock | SV Sandhausen | 0-1 | 2 - 4 points |
| 05/11/22 12:00 | 05/11/22 11:45 | Karlsruher SC | Holstein Kiel | 1-4 | 2 - 4 points |
| 05/11/22 12:00 | 05/11/22 11:45 | Fortuna Düsseldorf | FC St. Pauli | 1-0 | 2 - 4 points |
| 05/11/22 12:00 | 05/11/22 11:45 | 1. FC Heidenheim 1846 | SC Paderborn 07 | 3-0 | 2 - 4 points |
| 05/11/22 19:30 | 05/11/22 19:15 | Arminia Bielefeld | 1. FC Kaiserslautern | 2-3 | 2 - 4 points |
| 06/11/22 12:30 | 06/11/22 12:15 | Hamburger SV | Jahn Regensburg | 3-1 | 2 - 4 points |
| 06/11/22 12:30 | 06/11/22 12:15 | 1. FC Nürnberg | 1. FC Magdeburg | 1-2 | 2 - 4 points |
| 06/11/22 12:30 | 06/11/22 12:15 | Eintracht Braunschweig | SpVgg Greuther Fürth | 0-1 | 2 - 4 points |